Digital BW, The Print

Hi,

Can I work in Gray Lab even if the image might end up in ImagePrint ?

After I scan and process my negs I would like an option of using
either QTR or IP. (I used to work in Gray Gamma 2.2). 

Are there any advantages/pitfalls when making Gray Lab a space for all
B&W work or is it meant to be used only in conjuction with Gray
Matte/Photo profiles ?

TIA,

Roman