Digital BW, The Print

I know that we should generally print files (On the Epson) with a resolution at or near 350 
PPI. My question is what are the negative effects of using a higher resolution? If I opt not to 
throw out any data when re-sizing an image and the resolution ends up around 450 PPI, 
will this give me a lesser image than if I down-sized to 350?

Thanks - Ben