Digital BW, The Print

The following was posted on the QTR site, but thought I'd give it a 
shot here also:

I'm using an Epson R2400 printer. QTR offers so many printing
resolution options that I don't know where to begin.

I'll mostly be printing on 8.5 x 11 matte paper. I'm after quality. I'm 
not
particulary interested in saving ink, but I don't want to use settings
which will result in "overkill."

(This is my first week with QTR so any help would be very much 
appreciated).

Norm