Digital BW, The Print

I have finally successfully made and used profiles for printing
through the Epson ABW driver (on a 3800), but I have one more question. 

If I make one profile with setting ABW Dark, and another with ABW
Normal, all other driver settings the same, and then print the same
image from Photoshop first using one profile and then the other with
the driver settings appropriate to each, of course on the same paper,
will I see any difference in the print? That is, will Photoshop
compensate for the different tonality the driver is putting out or
will there still be differences?

Thanks for your help past and present with this fairly arcane topic.

  - susan