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Digital BW, The Print

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Re: [Digital BW] Re: Diluting HP PK

2009-02-08 by Roger Sopher

Red cells have a net negative surface charge and repel each other. The
surface charge can be modified by the composition of the protein matrix
surrounding them. For example, if one has an acute inflammatory condition
the charge on the red cells is diminished and they tend to clump forming
larger ³particles² and fall out of suspension more rapidly. This is more or
less the basis for the old ESR (erythrocyte sedimentation rate) test. If the
problem were in the concentrate then it might be possible to find a
suspending medium that would increase the surface charge on the particles.
In a dilute system that would have little or no effect. Sounds to me that
diluting eboni is fighting physics. I suppose it would be possible to boost
the viscosity of the suspending fluid but that would open a whole other can
of worms and would only slow not solve the sedimentation problem.

Roger



From: pr_roark <pr_roark@...>
Reply-To: DigitalBlackandWhiteThePrint
<DigitalBlackandWhiteThePrint@yahoogroups.com>
Date: Sun, 08 Feb 2009 17:38:34 -0000
To: DigitalBlackandWhiteThePrint
<DigitalBlackandWhiteThePrint@yahoogroups.com>
Subject: [Digital BW] Re: Diluting HP PK

 
 




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