Datacolor User to User Support Group.

I've just received PrintFix Pro and I've a question using it with the 
Epson R2400.It's known that in the R2400 printer driver you can choose 
different settings refferring to different DPI.usually i pick "Best 
Photo" (2880 DPI) and sometimes "RPM" (5760 PPI).What is advisable to 
pick, printing the PrintFix Pro targets (and then using the profiles)?
Is there any real difference in the quality of the profiles? Or is it 
advisable to make different profiles for each different DPI?
Thank you in advance

Luca