I posted this question a while back w/ no responses, so I thought I'd try again. The 2101 manual (v3.0 software) describes a setup where you use both the 2101 preamp and the guitar amp preamp (i.e., my Marshall) but using a "y cord" and the FX Loop Sum, No Sum, and Bypass modes so that you always have the digital effects in the effects loop of the guitar amp, but you can select which preamp is being used (the 2101 or the amp's). I have had little luck with the setup. Doing it exactly like the manual says does give very good results. The preamps are never separated and always seem to run simultaneously, regardless of settings (although which is most prevalent DOES changes depending on the FX loop control). What I'm looking to do in keep the digital effects in the effects loop of the marshall, but be able to select the 2101 preamp when I want it and keep it out of the way when I don't. As with most front end "boxes," the 2101 seems to greatly reduce the effect the guitar volume has on the tone of the amp (that is, you can't really go from clean to crunch on the amp using the guitar's volume with the 2101 preamp on the front end). Anybody ever successfully conquered this setup? I'd love to hear from ya. BTW, I run an '82 American Strat w/ EMGs (Gilmour set) and an Epi Les Paul (w/ Duncans) into the 2101 (v3.0) then into a Marshall DSL201 (20watt 1x12 combo, channel switching, single input [hence the y adapter needed for the manual's set up]). The DSL201 is great because you can drive the power tubes (2xEL84) to max without killing all carbon-based life forms within a 2 mile radius. Greg USA
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the "dual preamp" 2101 connection method
2002-07-05 by sbaalgmc
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