Digital BW, The Print

sorry if this is obvious to everyone---but, downloaded the OPM and 
found that it is sharper and finer than the piezo plug. I am using 
g3/500 9.2.2, 1280, MIS FS.
The files that print pretty well with PZO print light on OPM. I 
reprinted 21 step with opm, changed my dot gain to match, readjusted 
the picture files and I think they print kind of muddy---. What is 
the work flow with OPM? Do I need to do anything to the EPSON profile 
box or does OPM set the parameters of the printer? What about monitor 
proofing? Use the same settings as PZO or what? In other words: what 
is the "normal" workflow with this OPM-thanks, Jack