Digital BW, The Print

Help!

I've been happily printing all day, when suddenly I started getting "invalid printer settings" 
in my Quad2200 printer status window. 

I'm using Mac OS X and printing from Photoshop CS onto Epson Enhanced Matte, using a 
50-50 blend "UC-EEnhMatte-cool-1" and "UC-OrientalFB-warm-1.txt" using Matte Paper / 
Photography  / Seven Color Photo settings.

I checked the carts-- there's plenty of ink left in them. I even went so far as to reinstall 
everything but I am getting the same error message. I can no longer print.

Has anyone else ever encountered this problem?