Digital BW, The Print

Can anyone please advise on the relative merits of the various image 
forms from the scanning stage to the creation of a good quality B&W 
digital image? 

The original image would be either a mono negative, colour negative, 
colour slide or B&W chromogenic.

I'm interested in tonality and sharpness.
Assume the original would be a 120 film.
The scanner is a 4800 dpi Epson flatbed.

Many thanks everyone.