QTR-Quadtone RIP

I have created some icc profiles with QTR-Create_ICC.app using readings of my final print 
out of the 21-step wedge after linearization using no color management for my warm and 
cool curves; I also plan on doing some others for varying degrees in between my cool and 
warm.  I have seen the immediate benefit of these icc profiles for soft proofing.

As far as using them for printing I have some questions.  First when using these icc 
profiles for printing, I'm assuming that you use them with the Epson driver or other RIPs 
for the printer you are using; is my assumption correct?  Second, can you use them when 
printing through QTR, and if so, do you use them in conjunction with the same curve 
settings as was used to create the icc profile???  And if you can print with the icc profiles 
through QTR what are the advantages of doing so???

Another question I have is about the other ICC application with QTR, QTR-Create_ICC-
RGB.app.  Ii is my understanding that this application is for creating icc profiles with ACV 
curve adjustments to adjust the tone.  I'm not sure what the advantages of doing so; so if 
someone could explain I would appreciate this.  I'm also assuming that this is also only for 
when using full color inksets and not for use with gray scale inksets.  I'm guessing the 
advantage is when using full color inksets is that you would be able achieve any tone 
desirable and the tones should match a calibrated monitor.  

Thanks in advance for your comments,
Randy