Hi, unless the firmware is rewritten [like it has been done for the Amiga], then it will not work in anything that does not work with PC format 1.44MB disk format, of which the AKAI S series is not. They WILL work in the MPC2000/XL and the S5000 as these use standard format.
There is a 720k variant will work with the AKAI MPC60 and MPC3000/LE but I'm afraid that is all they will work on. But you have to buy the specific 720k version, the 1.44MB standard type cannot be modified to work as a 720k version as it has a different sized cache ram chip installed. Some say a jumper can be used to select density, but this does not work. tried and tested.
Chris.