Datacolor User to User Support Group.

Can someone please advise me on this problem?

I've profiled my LCD monitor with Spyder 2 Pro V2.2, and on booting 
Windows XP I get the Colorvision box telling me that the profile has 
been loaded to the Video card.

Fine ..... but some random time later the Monitor just flips back to 
it's uncalibrated setting, and to regain calibration I have to reboot.

Using the Colourvision Profile chooser and clicking refresh doesn't 
have any effect.

Also, I've downloaded and installed Windows Color Manager 2.0. This 
shows the relevant profiles, but the "Apply" button is greyed out, so I 
can't use this either.

Any ideas as to what the problem is, anyone?